The greater grison (Galictis vittatta) is one of the least studied Neotropical carnivores. As part of a biodiversity survey in southeastern Mexico, we recorded in a camera trap a greater grison that carried in its mouth a Central American indigo snake (Drymarchon melanurus). Even though we did not find evidence that the snake was consumed by the greater grison in place, it is likely that the species carried the snake to a refuge to be eaten as previously reported with other large prey. If confirmed, this would be the first time that the greater grison has been documented hunting and probably feeding on snakes in Mexico and elsewhere.