Lymphoma is a common malignancy observed in companion animals. This type of naturally occurring neoplasia has been uncommonly reported in great apes. Diffuse large B-cell lymphoma was diagnosed in an 8-yr-old captive orangutan (Pongo pygmaeus) with gastrointestinal disease by histologic and immunohistochemical methodologies. The orangutan was treated with three cycles of combination chemotherapy (intravenous Rituxan, cyclophosphamide, doxorubicin, and vincristine). The primate has been in good health and exhibiting normal behaviors for more than 15 mo following treatment.
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1 December 2014
DIAGNOSIS AND TREATMENT OF DIFFUSE LARGE B-CELL LYMPHOMA IN AN ORANGUTAN (PONGO PYGMAEUS)
Offiong F. Ikpatt,
Drury Reavill,
Jason Chatfield,
Susan Clubb,
Joseph D Rosenblatt,
Glenn Fonte,
Yao-Shan Fan,
Carolyn Cray
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immunohistochemistry
Intestine
lymphoma
nonhuman primate
orangutan
Pongo pygmaeus