Mosqutio larvicidal activity of Chamaecyparis obtusa leaf-derived materials against the 4th-stage larvae of Aedes aegypti (L.), Ochlerotatus togoi (Theobald), and Culex pipiens pallens (Coquillett) was examined in the laboratory. A crude methanol extract of C. obtusa leaves was found to be active (percent mortality rough) against the 3 species larvae; the hexane fraction of the methanol extract showed a strong larvicidal activity (100% mortality) at 100 ppm. The bioactive component in the C. obtusa leaf extract was characterized as β-thujaplicin by spectroscopic analyses. The LC50 value of β-thujaplicin was 2.91, 2.60, and 1.33 ppm against Ae. aegypti, Oc. togoi, and Cx. pipiens pallens larvae. This naturally occurring C. obtusa leaves–derived compound merits further study as a potential mosquito larval control agent or lead compound.
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1 December 2005
MOSQUITO LARVICIDAL ACTIVITY OF ACTIVE CONSTITUENT DERIVED FROM CHAMAECYPARIS OBTUSA LEAVES AGAINST 3 MOSQUITO SPECIES
YOUNG-SU JANG,
JU-HYUN JEON,
HOI-SEON LEE
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Journal of the American Mosquito Control Association
Vol. 21 • No. 4
December 2005
Vol. 21 • No. 4
December 2005
Aedes aegypti
Chamaecyparis obtusa
Culex pipiens pallens
mosquito larvicide
Ochlerotatus togoi
β-thujaplicin