Iguana iguana is a well-established introduced species in southern Florida, including a large population on Key Biscayne. In its native range, I. iguana is known to be almost strictly herbivorous. Juveniles are often reported to be somewhat omnivorous, but prey items are rarely identified. The tree snail Drymaeus multilineatus is common in southern Florida, where it is found on stems and leaves and in edificarian habitats. The examination of I. iguana stomachs from Bill Baggs Cape Florida State Park, Key Biscayne, resulted in the discovery of D. multilineatus in two lizards, including 12 snails in one juvenile I. iguana. The large and rapidly growing I. iguana populations in southern Florida may have the potential to devastate some highly localized native species of tree snails.