The genus Akalyptoischion Andrews is revised to include 24 species, 16 of which are new. A taxonomic treatment of the genus is provided including a morphological study, new species descriptions, keys, illustrations, and notes on the distribution and biology of Akalyptoischion. The following species are included: A. anasillos Andrews, USA, CA; A. atrichos Andrews, USA, CA; A. bathytrematosnew species, Mexico, Baja California; A. chandleri Andrews, USA, AZ; A. delotretosnew species, USA, CA, NV; A. diadeletronnew species, USA, OR, ID; A. dyskritosnew species, USA, UT; A. echinosnew species, USA, CA; A. gigasnew species, USA, CA; A. giulianii Andrews, USA, CA; A. hadromorphusnew species, USA, CA; A. heptalocosnew species, Mexico, Baja California; A. heterotrichosnew species, USA, CA; A. hormathos Andrews, USA, CA; A. lasiosusnew species, USA, CA; A. leptosomanew species, USA, CA; A. parechinosnew species, USA, CA; A. pogoniasnew species, USA, CA; A. polytremetronnew species, USA, AZ; A. prionotusnew species, USA, CA; A. quadrifoveolata (Fall), USA, CA; A. sleeperi Andrews, USA, CA; A. texasnew species, USA, TX; A. tomeus Andrews, USA, CA.