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1 December 2004 There Is No Denying This: Defusing the Confusion about Atrazine
TYRONE B. HAYES
Author Affiliations +
Abstract

Recent studies from my laboratory, showing the chemical castration (demasculinization) and feminization of amphibians by low but ecologically relevant concentrations of atrazine in the laboratory and in the wild, prompted a critical response from atrazine's manufacturer, Syngenta Crop Protection, and Syngenta-funded scientists. A careful analysis of the published data funded by Syngenta, and of several studies submitted to the US Environmental Protection Agency (EPA) by the Syngenta-funded panel for data evaluation, indicates that the data presented in these studies are not in disagreement with my laboratory's peer-reviewed, published data. Further, the published and unpublished data presented to the EPA by the Syngenta-funded panel (and touted in the popular press) suffer from contaminated laboratory controls; high mortality; inappropriate measurements of hormone levels in stressed, sexually immature animals during nonreproductive seasons; and contaminated reference sites. The confounding factors in the industry-funded studies severely limit any conclusions about the adverse effects of atrazine on amphibians and prevent meaningful comparisons with my laboratory's published data.

TYRONE B. HAYES "There Is No Denying This: Defusing the Confusion about Atrazine," BioScience 54(12), 1138-1149, (1 December 2004). https://doi.org/10.1641/0006-3568(2004)054[1138:TINDTD]2.0.CO;2
Published: 1 December 2004
JOURNAL ARTICLE
12 PAGES

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KEYWORDS
amphibian
atrazine
Chemical castration
endocrine disruptor
feminization
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