Thirty-nine free-ranging raccoons (Procyon lotor) in an endemic rabies area of Pennsylvania (USA) were vaccinated with a single intramuscular inoculation of commercial inactivated rabies virus vaccine, 17 June to 23 August 1987. Paired serum samples, pre- and postvaccination, were obtained from eight raccoons and were analyzed in vitro for rabies virus neutralizing antibody using a modified rapid fluorescent focus inhibition test. Seven of eight (88%) recaptured raccoons demonstrated seroconversion within 15 to 26 days of vaccination. At 1 yr postvaccination, three vaccinated raccoons were recaptured and challenged in captivity with street rabies virus, resulting in the death of two of three vaccinates and five of five unvaccinated control raccoons.
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1 April 1990
Vaccination of Free-Ranging Pennsylvania Raccoons (Procyon lotor) with Inactivated Rabies Vaccine
Clifford L. Brown,
Charles E. Rupprecht
Journal of Wildlife Diseases
Vol. 26 • No. 2
April 1990
Vol. 26 • No. 2
April 1990
experimental study
hand immunization
oral immunization
Procyon lotor
rabies
rabies control
raccoon